The hooded duo armed with a black handgun and a kitchen knife entered the Co-op store at Westhorne Avenue in Eltham at about 10.30pm on July 31.
One supermarket worker appears to hit the panic alarm before the other is forced to open the till and hand over the cash.
The female shop assistant is seen pleading with the two armed men saying: “I don’t have any money, I don’t have any money.”
“I don’t have any money, I don’t have any money”
One of the robbers taps the large blade on the counter menacingly while the other shouts: “Open the till, open the till now”.
The knifeman then moves behind the till to stash cigarette packets into a JD Sports bag.
In the video the male shopkeeper hands over the cash.
During the robbery one of the masked men keeps a gun pointed at the two co-workers.
Both men then left the store and fled in a waiting white Range Rover Evoque, which was driven by another suspect.
Met Police have released the footage of the raid, in which nobody was injured, and hope to identify the two suspects.
Detectives said the first suspect armed with a knife is described as a black man and aged between 18 and 22.
He wore a dark Ralph Lauren hooded jumper, dark Ralph Lauren tracksuit bottoms, dark Nike cap and a black balaclava.
The suspect armed with a handgun is described as a white male, aged between 18 and 22.
He was wearing black, knee-length, tracksuit bottoms, white socks pulled up and black trainers and a navy blue Nike hooded top.
Anyone who has information or who could identify those involved should call the incident room for Flying Squad East on 020 8345 1400 or 101 or Crimestoppers anonymously on 0800 555 111.